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For instance, exendin-4 has been shown to ameliorate the high glucose-induced fibronectin (FN) and type I collagen (Col1) expression in tubular epithelial cells by inhibiting the secretion of miR-192, an microRNA (miRNA) that is regulated by p53 and plays a role in renal fibrosis (Yin et al., 2018)

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The relative standard deviation (RSD) of the parallel operation was 1.63%

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Am J Nephrol 29:551557 Perticone F, Sciacqua A, Maio R, Perticone M, Maas R, Boger RH, Tripepi G, Sesti G, Zoccali C (2005) Asymmetric dimethylarginine, L-arginine, and endothelial dysfunction in essential hypertension

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The most common of them include Cu 2+ /Zn 2+ superoxide dismutase 1 ( SOD1 ), TAR DNA-binding protein 43 ( TARDBP) , fused in Sarcom a ( FUS ) , and chromosome 9 open reading frame 72 ( C9orf72) genes, involved in protein homeostasis and RNA metabolism [72,73,74,75]

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