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For example in some \(\pi\) complexes like \(\eta\) 5 -Cp 4 U technically there are 20 C atoms fastened to the U but these complexes are better considered as 12 coordinate than twenty (since each cyclopentadienl ring is isolobal with a fac coordinated set of 3 L ligands) while the metal centers in endohedral fullerene species like La@C 60 do not interact with all sixty carbon atoms at once are so are better thought of as a metal trapped in a spacious sixty-carbon cage

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Weeks 8-12 : More significant improvements in deeper wrinkles, continued collagen density increase, improved skin thickness (measured via ultrasound in clinical settings), and sustained reduction in age-related skin laxity