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Similarly, in a randomized case-crossover field trial, US smokers reported higher negative effects toward smoking, self-efficacy to quit, response efficacy beliefs, and motivation to quit in the week when their packs included inserts 13

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Gonzalez-Suarez I, Martin F, Marescotti D, Guedj E, Acali S, Johne S, Dulize R, Baumer K, Peric D, Goedertier D, Frentzel S, Ivanov NV, Mathis C, Hoeng J, Peitsch MC (2016) In vitro systems toxicology assessment of a candidate modified risk tobacco product shows reduced toxicity compared to that of a conventional cigarette