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Food and Drug Administration (FDA) set a minimum legal sale age of 18 and forbade free e-cig samples, which were being distributed at music and sporting events

Randomisation A simple randomisation sequence was generated by a senior statistician (RM) not involved with recruitment or data collection

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The distinct qualities of Perique dont just come from a rare variety of tobacco, but traditional farming methods and skillful processing techniques along with a years aging in oak barrels